Tumor Type Tissue of Origin Bone Chondrosarcoma Cartilage Osteosarcoma Bone Ewing's sarcoma Probably neural crest (primitive nerve) Fibrosarcoma Connective (fibrous) tissue Soft Tissue Fibrosarcoma Connective (fibrous) tissue Liposarcoma Fat Rhabdomyosarcoma Skeletal muscle Synovial sarcoma Membranes lining joints Neurofibrosarcoma Nerve structures Angiosarcoma Blood vessels Leiomyosarcoma Smooth muscle, such as found in the wall of the bowel